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Clear Change Daily Essentials, 30 Daily Pack

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Provides antioxidants and factors for good health, and detoxification.


  • Nutrients: vitamins, minerals, antioxidants
  • Detoxification & Glutathione Synthesis

Feature Ingredients

  • NAC (N-Acetyl-Cysteine) – increases the production of glutathione the body’s master antioxidant.
  • Other vital nutrients that promote detoxification, blood guar regulation, and metabolic function include green tea extract, taurine, glutathione, chromium picolinate and magnesium citrate.

Clear Change Daily Essentials is a premium packet containing 3 nutritional supplements designed to complement your daily foundation nutrition program and support daily detoxification following the Clear Change Metabolic Detoxification Program. This 1-month program features AdvaClear®, GlutaClear®, and Renagen DTX for targeted, daily support.*

Each once-daily packet provides:

  • Bifunctional detoxification support: AdvaClear® promotes vitality and health by supporting balanced activity of the Phase 1 and Phase 2 detoxification pathways. This formula provides methylated vitamin B12 and folic acid along with nutrients designed to enhance the activities of several liver detoxification enzymes.*
  • Antioxidant protection & detoxification support: GlutaClear® features a blend of key ingredients, including antioxidant vitamins, designed to help boost the body’s production of glutathione. Glutathione plays an important role in protecting the body against oxidative stress and protecting cellular health.*
  • Kidney health: Renagen DTX is a specific blend of nutrients and traditional herbs designed to support healthy kidney function.*

      Serving Size: 1 Daily Pack

      Servings per Container: 30

      Medicinal Ingredients

      Ingredient Amount Daily Value
      Artichoke (Cynara scolymus L.) 10:1 leaf extract equivalent to 830 mg of artichoke 83 mg   
      Vitamin C (ascorbic acid) 66 mg   
      Watercress (Nasturtium officinale) 4:1 aerial parts extract equivalent to 264 mg of watercress 66 mg   
      Taurine 58 mg   
      Milk Thistle (Silybum marianum) seed extract standardized to 50% silymarin 50 mg   
      Pomegranate (Punica granatum) 9:1 whole fruit extract equivalent to 378 mg of pomegranate 42 mg   
      N-Acetylcysteine 33 mg   
      Green Tea (Camellia sinensis) leaf extract standardized to 60% catechins and 40% EGCG 28 mg   
      Vitamin E (d-alpha tocopheryl succinate) 22 mg   
      Pantothenic Acid (calcium d-pantothenate) 16.5 mg   
      Vitamin B6 (pyridoxine HCl) 8 mg   
      Niacinamide 6.6 mg   
      Thiamin (thiamin mononitrate) 5 mg   
      Niacin 5 mg   
      Zinc (zinc citrate) 3 mg   
      Riboflavin 2.5 mg   
      Manganese (manganese citrate) 0.83 mg   
      Beta-Carotene 500 mcg   
      Copper (copper citrate) 0.33 mg   
      Folate (calcium L-5-methyltetrahydrofolate) 134 mcg   
      Vitamin A (retinyl palmitate) 125 mcg   
      Molybdenum (hydrolyzed vegetable protein) 33 mcg   
      Biotin 33 mcg   
      Selenium (selenomethionine) 25 mcg   
      Vitamin B12 (methylcobalamin) 16.6 mcg   
      Vitamin D (cholecalciferol) 0.42 mcg   
      GlutaClear – NPN 80049046
      Ingredient Amount Daily Value
      N-Acetylcysteine 375 mg   
      Niacinamide 375 mg   
      Vitamin C (ascorbic acid) 250 mg   
      Brocolli seed extract (Brassica oleracea var. italica) (2.5 mg sulforaphane glucosinolate) 19.25 mg   
      Selenium (selenomethionine) 37.5 mcg   
      KD Plus – NPN 80050486
      Ingredient Amount Daily Value
      N-Acetylcysteine 200 mg   
      Cordyceps (Cordyceps sinensis) mycelium extract standardized to 0.25% adenosine 200 mg   
      Chinese Salvia (Salvia miltiorrhiza) 8:1 root extract equivalent to 1,600 mg of chinese salvia 200 mg   
      Vitamin B6 (pyridoxine HCl) 10 mg   
      Folate (calcium L-5-methyltetrahydrofolate) 400 mcg   
      Vitamin B12 (methylcobalamin) 125 mcg   

      Non-Medicinal Ingredients

      • AdvaClear: Hypromellose, cellulose, sodium sulfate, magnesium stearate (veg), and silicon dioxide.
      • GlutaClear: Cellulose, stearic acid (veg), silicon dioxide, and coating (hypromellose, hydroxypropylcellulose, and medium-chain triglycerides).
      • KD Plus: Hypromellose, cellulose, and magnesium stearate (veg).


      Contains No: artificial colours, preservatives, or sweeteners;  wheat, gluten, or GMOs.  

      Recommended Use

      Adults 19+:  Take 1 packet (2 AdvaClear, 1 GlutaClear, 1 KD Plus) daily with meals providing protein or as directed by your healthcare practitioner. Take a few hours before or after taking other medications.

      Metagenics Naturals Advantage

      Each Clear Change Daily Essentials formula is science based and delivers optimized, targeted health support.


      Adult use only. Do not use if you are hypersensitive or allergic to any of the ingredients, pregnant or breast-feeding, bile duct obstruction, have a bleeding disorder, or are allergic to plants of the Asteraceae/Compositae/Daisy family.

      Do not use if taking blood thinning medications, antihypertensive medications, nitroglycerine, antibiotics, hypoglycemic medications and insulin, digoxin or nitroglycerin, or before surgery.


      Consult a health care practitioner prior to use if you are taking any medications, or if you have any pre-existing condition including but not limited to: autoimmune disorder, bleeding disorder, kidney -including kidney stones, gallstones, an iron defciency, cystinuria, liver disorder or develop symptoms of liver trouble (such as abdominal pain, dark urine or jaundice), a lung disorder, or if symptoms persist or worsen. Discontinue 2 weeks prior to surgery.

      Consult a healthcare practitioner, if taking blood thinners, immunosuppressive medications, or for use beyond 3 months. 

      Metafolin® is a registered trademark of MerckKGaA, Darmstadt Germany

      Side Effect Risks

      Discontinue use and consult a healthcare practitioner if symptoms persist, worsen or you develop any reactions which may include: allergy or intolerance, or digestive (bloating, cramping, gas, diarrhoea). People sensitive to nicotinic acid may experience flushing of the skin that is generally mild and transient. Keep out of reach of children. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.


      The information and product descriptions that appear on this website are for information and educational purposes only and are not intended to provide or replace medical advice to individuals from qualified health care professionals. Consult your physician if you have any health concerns, and before initiating any new dietary, exercise, supplements or other lifestyle changes.