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GI-Soothe 60 Veg Caps, Cytomatrix

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A blend of three demulcent herbs to effectively reduce inflammation and irritation to the digestive tract lining.
  • Provides a blend of deglycyrrhizinated licorice root (DGL), marshmallow root and slippery elm in highly potent extracted forms
  • Indicated for reducing inflammation and irritation to the digestive tract lining, including gastritis, reflux esophagitis and irritable bowel syndrome, and preventing damage to the digestive tract as a result of anti-inflammatory medications



Irritation to the digestive tract lining can occur under many circumstances, leading to inflammation and symptoms of abdominal pain, heartburn, gas, bloating, irritable bowel syndrome and more. Traditionally, specific herbs have been used to soothe and coat the gastrointestinal lining under such circumstances, providing a mucoprotective action. These herbs are known as demulcents.

Demulcents are effective in treating diarrhea, constipation and inflammatory conditions of the gastrointestinal tract. They act by preventing microbe binding to cell membranes, binding excessive water, improving microcirculation and acting as a direct physical barrier in the digestive tract. Deglycyrrhizinated licorice (DGL), Althea officinalis (marshmallow root) and Ulmus rubra (slippery elm) are some of the most well-established demulcents with clinical efficacy.

DGL is a form of licorice root that has removed glycyrrhizin, a constituent that is responsible for increasing cortisol and fluid retention. This allows for a soothing effect on the gastrointestinal lining with minimal safety concerns. DGL has been studied for its ability to effectively treat the symptoms associated with damaged gastric and duodenal linings. Moreover, chewing DGL has also shown to have a positive effect on the gastrointestinal mucosa and some evidence suggests that DGL can help to prevent damage to the digestive tract lining caused by non-steroidal anti-inflammatory drugs (NSAIDs). Marshmallow root and slippery elm have anecdotally been used for decades as safe and effective demulcents to treat reflux esophagitis, gastritis, diarrhea, respiratory concerns and even inflammatory skin lesions.

GI-Soothe provides DGL, marshmallow root and slippery elm in high-potency extracts for effective demulcent and mucoprotective effects on the gastrointestinal tract. Available in 60 vegetable capsule bottles.

Ingredient Amount
DGL (root, Deglycyrrhizinated licorice) 10:1, DHE 2250mg 225mg
Marshmallow extract (root, Althea officianalis) 20:1, DHE 5000mg 250mg
Slippery Elm extract (bark, Ulmus rubra) 4:1, DHE 1000mg 250mg

Unit of Measure above: Each capsule

Non-Medicinal Ingredients: Vegetable-grade magnesium stearate. Capsule: hypromellose.


Vegan. GMO, gluten, soy and dairy free.

Recommended Use 

Indications: Traditionally used in Herbal Medicine to relieve mild inflammation of the gastro-intestinal mucosa (e.g. gastritis), irritation of the oral and pharyngeal mucosa and associated dry cough. Used in Herbal Medicine as a demulcent to help relieve abdominal pain and burning sensation in the stomach.

Directions for Use: Adults - Take 1 capsule, 2 times per day or as directed by a healthcare professional. Take a few hours before or after other medications or natural health products.

Cytomatrix Advantage 

The excellent clinical results that are achieved with our products, combined with our honest and ethical approach, has earned Cyto-Matrix the trust of many of the most scrutinizing Canadian healthcare practitioners. We are appreciative and honoured that new clients of Cyto-Matrix quickly become loyal clients and are open to building a lasting relationship with us.


Do not use if you are hypersensitive or allergic to any of the ingredients. Do not use if you are pregnant or breastfeeding, or if you have high blood pressure, bipolar disorder or bipolar spectrum disorder.


Consult a health care practitioner prior to use if you are taking any medications or if you have any pre-existing condition or symptoms. Consult a healthcare professional prior to use of this product if you are taking any prescription medications including antidepressants, hormone replacement therapy, birth control pills or if you have any medical condition including an autoimmune disorder, an acute infection, or if you are following a low protein diet. Consumption with alcohol, other drugs or natural health products with sedative properties is not recommended. Discontinue 2 weeks prior to any scheduled surgery.

Side Effect Risks

Discontinue use and consult a healthcare practitioner if symptoms persist, worsen or you develop any reactions which may include: allergy or intolerance, or digestive irritation (bloating, diarrhea, nausea,).Keep out of reach of children. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.


The information and product descriptions that appear on this website are for information and educational purposes only and are not intended to provide or replace medical advice to individuals from qualified health care professionals. Consult your physician if you have any health concerns, and before initiating any new dietary, exercise, supplements or other lifestyle changes.