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Grapefruit Seed Extract With Wormwood 405mg, 90 Caps, Vitazan

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A professional supplement that may support immunity and provide antimicrobial action.


  • Immunity
  • Nutrients: Antioxidants, Vitamins C & E
  • Digestion

Feature Ingredients

  • Grapefruit Seed Extract (GSE) is rich in nutrients and may help to support immunity and provide antimicrobial activity.


Echinacea angustifolia is a herbal from the daisy family. A 2016 meta-analysis found that Echinacea extracts may reduce the risk of repeated respiratory infections.1 A 2015 monograph by the European Medicines Agency stated that oral consumption of "expressed juice" or dried expressed juice of Echinacea could prevent or reduce symptoms of a common cold at its onset. 2

Wormwood is used in traditional herbal medicine as a bitter tonic to stimulate appetite and as a vermifuge to help with the expulsion of intestinal parasites such as pinworms and roundworms.


Grapefruit seed extract (GSE), also known as citrus seed extract, is an extract derived from the seeds, pulp, and white membranes of grapefruit.  GSE is rich in the phytochemicals:  flavonoids, ascorbic acid (vitamin C), tocopherols, citric acid, limonoids, sterols and minerals.3-6 It’s also rich in essential oils and antioxidants and has a variety of potential health benefits which include:

  • Antimicrobial Action – GSE contains potent compounds that have antimicrobial action of more than 60 types of bacteria and yeast.7,8 Test-tube studies have shown that it can even be as effective as some commonly prescribed topical antifungal and antibacterial medications, such as nystatin7. GSE works to kill bacteria by breaking down their outer membranes, causing them to burst open after just 15 minutes of exposure.9
  • Antioxidant Support - The polyphenol naringin is found in very high concentrations in grapefruit seeds and is what gives grapefruit its bitter taste.11 Naringin has strong antioxidant abilities and has been found to protect tissues against radiation damage in animal studies.12
  • Digestion Support – Animal studies have found GSE to be protective of the stomach from damage caused by alcohol and stress. 13 It may protect the stomach lining from ulcers and other lesions by increasing blood flow to the area and preventing free radical damage. 13 GSE has also found to have antimicrobial activity against pylori, which is associated with GERD, stomach inflammation and ulcers. 14
  • Other – Early research suggests that GSE may help to reduce urinary tract infections, heart disease and improve blood sugar regulation.

While grapefruit seed extract appears to be beneficial in animals and test-tube studies, human research is not presently available.


Serving Size: 5 Vegetarian Capsules (twice daily)

Servings per Container:  45 (22.5 daily doses)

Medicinal Ingredients

Each Capsule Contains:

Echinacea (Echinacea angustifolia) root

161 mg

Wormwood (Artemisia absinthium) aerial parts

161 mg

Grapefruit seed extract

84 mg

Non-Medicinal Ingredients

Silicon dioxide and vegetable magnesium stearate in a non‑GMO vegetable capsule composed of vegetable carbohydrate gum and purified water.


Contains No Added: wheat, yeast, gluten, artificial colouring or flavouring, or dairy products.

Recommended Use

Adults 19+:  Take 5 capsules twice daily or as directed by your health-care practitioner. Consult a health-care practitioner for use beyond 1 month.

Vitazan Advantage

Vitazan is a supplement company that is dedicated to research and high-quality products available through professionals only.


Do not use if you are hypersensitive or allergic to any of the ingredients. Do not use if you are using medication in which grapefruit is contraindicated.


Consult a health care practitioner prior to use if you are taking any *medications (including but not limited to blood thinners or cardiovascular drugs in which grapefruit is contraindicated), or if you have any pre-existing condition. Do not exceed the recommended dose. Discontinue this product 2 weeks prior to surgery.

Other drugs may interact with this product, including prescription and over-the-counter medicines, vitamins, and herbal products.

Side Effect Risks

Discontinue use and consult a healthcare practitioner if symptoms persist, worsen or you develop any reactions which may include: allergy or intolerance or digestive upset (constipation, nausea, vomiting). Keep out of reach of children. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.


The information and product descriptions that appear on this website are for information and educational purposes only and are not intended to provide or replace medical advice to individuals from qualified health care professionals. Consult your physician if you have any health concerns, and before initiating any new dietary, exercise, supplements or other lifestyle changes.


  1. Schapowal A, Klein P, Johnston SL (March 2015). "Echinacea reduces the risk of recurrent respiratory tract infections and complications: a meta-analysis of randomized controlled trials". Advances in Therapy. 32 (3): 187–200.
  2. "European Union herbal monograph on Echinacea purpurea (L.) Moench, herba recens" (PDF). Committee on Herbal Medicinal Products, European Medicines Agency. 24 November 2015. Retrieved August 29,2020
  1. Eleraky NZ, Potgieter LN, Kennedy MA (2002). "Virucidal efficacy of four new disinfectants". J Am Anim Hosp Assoc. 38 (3): 231–4.
  2. Drewnowski A, Gomez-Carneors C (2000). "Bitter taste, phytonutrients, and consumer: a review". Am. J. Clin. Nutr. 72 (6): 1424–35.
  3. Tirillini B (2000). "Grapefruit: the last decade acquisitions". Fitoterapia. 71: 29–37.
  4. Bennett RD, Hasegava S, Herman Z (1989). "Glucosides of acidic limonoids in citrus" (PDF). Phytochemistry. 28 (10): 2777–81.
  5. Reagor L, Gusman J et al, The effectiveness of processed grapefruit-seed extract as an antibacterial agent: I. An in vitro agar assay, J Altern Complement Med. 2002 Jun;8(3):325-32.
  6. Cvetnic Z, and Vladimir-Knezevic S, Antimicrobial activity of grapefruit seed and pulp ethanolic extract, Acta Pharm. 2004 Sep;54(3):243-50
  7. Heggers JP, Cottingham J, et al, The effectiveness of processed grapefruit-seed extract as an antibacterial agent: II. Mechanism of action and in vitro toxicity, J Altern Complement Med. 2002 Jun;8(3):333-40.
  8. Cao S, Xu W, et al, A mitochondria-dependent pathway mediates the apoptosis of GSE-induced yeast, PLoS One. 2012;7(3):e32943
  9. Melesio Cristobal-Luna Jose, Gonzalez IA, et al, Grapefruit and its biomedical, antigenotoxic and chemopreventive properties, Food Chem Toxicol. 2018 Feb:112:224-234
  10. Jagetia GC, and Reddy TK, Modulation of radiation-induced alteration in the antioxidant status of mice by naringin, Life Sci. 2005 Jul 1:77(7):780-94
  11. Zayachkivska OS, Konturek Sj et al, Gastroprotective effects of flavonoids in plant extracts, J Physiol Pharmacol. 2005 Mar; 56 Suppl 1:219-31
  12. Guzeldag G, Kadioglu L, et al , Preliminary Examination of Herbal Extracts on the Inhibition of Helicobacter Pylori, Afr J Tradit Complement Altern Med. 2014; 11(1):93-96