Overview
100% spore-based, broad-spectrum probiotic clinically shown to maintain healthy gut barrier function.
Supports
Feature Ingredients
- Bacillus Licheniformis: Produces proteases needed for protein digestion and produces full spectrum of B vitamins.
- A combination of 5 bacillus probiotics: B licheniformis, B. Indicus HU36™, B. Subtilis HU58™, B. Clausii, and B. Coagulans
MegaSporeBiotic™ is a 100% spore-based, broad-spectrum probiotic clinically shown to maintain healthy gut barrier function. MegaSporeBiotic™ is the first 100% spore-based, broad-spectrum probiotic clinically shown to improve leaky gut by 60% in just 30 days. This unique all-spore formula effectively reconditions the gut by promoting microbial diversity and maintaining key health-promoting, commensal gut bacteria. MegaSporeBiotic™ boasts a 5-year shelf-life, does not require refrigeration, and maintains efficacy during antibiotic therapy.
The 1st probiotic to PROTECT its human host
- MegaSporeBiotic is a probiotic blend of 5 Bacillusspores that have been clinically shown to maintain healthy gut barrier function and overall immunity. The bi-phasic life cycle of the Bacillus spores allows them to remain dormant in harsh environments until they reach more favorable environments like the human gastrointestinal tract. Once inside the large intestine, these dormant spores can change into their active, vegetative forms and begin colonizing in the gut. This unique probiotic blend aims to RECONDITION the gut instead of reseeding with probiotic strains that cannot survive digestion or colonize the gut. MegaSporeBiotic has quickly become a household favorite among health practitioners and consumers alike.
- Bacillus Licheniformis: Produces proteases needed for protein digestion and produces full spectrum of B vitamins.
- Bacillus Indicus HU36™: Produces RDA levels of carotenoids: lycopene, astaxanthin, beta-carotene, and lutein; quinols and vitamins
- Bacillus Subtilis HU58™: Produces nattokinase and vitamin K2 and supports healthy GALT development
- Bacillus Clausii: Supports immune function and maintains efficacy during antibiotic treatment
- Bacillus Coagulans: Produces L+ optical form of lactic acid and supports immune function
Ingredients
Serving Size: 2 Capsules
Servings per Container: 30
Medicinal Ingredients
Each Capsule Contains: |
|
Proprietary Probiotic Blend |
340 mg 4 Billion CFU |
Bacillus indicus, HU36™ |
|
Bacillus subtilis, HU58™ |
|
Bacillus coagulans (SC-208) |
|
Bacillus licheniformis (SL-307) |
|
Bacillus clausii (SC-109) |
|
%Daily values not established. |
|
Non-Medicinal Ingredients
Cellulose, vegetable capsule (cellulose and water)
Allergens
Contains No Added: artificial coloring or flavoring, antimicrobial preservatives.
Recommended Use
Adults 19+ and Children 5+: Start with 1/2 capsule or 1 full capsule with food and slowly increase to 2 capsules per day using the following protocol.
If 1 capsule every other day is too strong, try starting with 1/2 capsules or even 1/4 capsule in some cases. Possible symptoms may include abdominal cramping, loose stools, and changes in bowel movements. Though these symptoms may be uncomfortable, they are a sign that the product is working! Symptoms should resolve within 2-3 days.
Microbiome Advantage
A company leader in probiotic research and formulation of the first all-spore probiotic known as MegaSporeBiotic.
Contraindications
Do not use if you are hypersensitive or allergic to any of the ingredients.
Caution
Consult a health care practitioner prior to use if you are taking any medications, or if you have any pre-existing condition including but not limited to: autoimmune disorder, pregnancy or breastfeeding. Discontinue this product 2 weeks prior to surgery.
Side Effect Risks
Discontinue use and consult a healthcare practitioner if symptoms persist, worsen or you develop any reactions which may include: allergy or intolerance, digestive (discomfort, gas, bloating). Keep out of reach of children. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.
Disclaimer
The information and product descriptions that appear on this website are for information and educational purposes only and are not intended to provide or replace medical advice to individuals from qualified health care professionals. Consult your physician if you have any health concerns, and before initiating any new dietary, exercise, supplements or other lifestyle changes.
References
- McFarlin BK, Henning AL, Carbajal KM. Oral spore-based probiotic supplementation was associated with reduced incidence of post-prandial dietary endotoxin, triglycerides, and disease risk biomarkers. World J Gastrointest Pathophysiol. 2017 Aug 15; 8(3): 117–126.
- Rhee KJ, Sethupathi P, Driks A, et al, ,Role of commensal bacteria in development of gut-associated lymphoid tissue and preimmune antibody repertoire. J Immunol. 2004;172(2):1118-24.
- De Punder K, Pruimboom L. Stress induces endotoxemia and low-grade inflammation by increasing barrier permeability. Front Immunol. 2015;15(6):223.
- Gong Y, Li H, Li Y. Effects of Bacillus subtilis on epithelial tight junctions of mice with inflammatory bowel disease. J Interferon Cytokine Res. 2016;36(2).
- Samanya M, Yamauchi K. Histological alterations of intestinal villi in chickens fed dried Bacillus subtilis var. natto. Comp Biochem Physiol A Mol Integr Physiol. 2002;133(1):95-104.
- Tam NKM, Uyen NQ, Hong HA, et al. The Intestinal Life Cycle of Bacillus subtilis and Close Relatives. Journal of Bacteriology. 2006;188(7):2692-2700.
- Survival of probiotics in simulated gastric fluid” Food Science Center Report. Silliker Labs. RPN 16663. August 24, 2013.
- Gibson GR, Rouzaud G, Brostoff J, et al, evaluation of probiotic effects in the human gut: microbial aspects. Final Technical report. FSA project ref G01022.
- Lefevre M, Racedo SM, Ribert G, et al. , Probiotic strain Bacillus subtilis CU1 stimulates immune system of elderly during common infectious disease period: a randomized, double-blind placebo-controlled study. Immun Aging. 2015;12:24.
- Serra CR, Earl AM, Barbosa TM, et al. Sporulation during Growth in a Gut Isolate of Bacillus subtilis. J Bacteriol. 2014;196(23):4184-4196.
- Hong HA, Khane JA R, Tam NMK , et al. Bacillus subtilis isolated from the human gastrointestinal tract. Res Microbiol. 2009;160(2):134-143.
- Mandel DR, Eichas K, Holmes J. Bacillus coagulans: a viable adjunct therapy for relieving symptoms of rheumatoid arthritis according to a randomized, controlled trial. BMC Complement Altern Med. 2010;10:1.
- Marseglia GL, Tosca M, Cirillo I, et al. Efficacy of Bacillus clausii spores in the prevention of recurrent respiratory infections in children: a pilot study. Ther Clin Risk Manag. 2007;3(1):13-7.
- Urdaci MC, Bressollier P, Pinchuk I, et al. Bacillus clausii probiotic strains: antimicrobial and immunomodulatory activities. J Clin Gastroenterol. 2004;38(6 Suppl):S86-90.
- Nista EC, Candelli M, Cremonini F, et al. Bacillus clausii therapy to reduce side-effects of anti-Helicobacter pylori treatment: randomized, double-blind, placebo controlled trial. Aliment Pharmacol Ther. 2004 Nov;20(10):1181-8.
- Gabrielli M, Lauritano EC, Scarpellini E, et al. Bacillus clausii as a Treatment of Small Intestinal Bacterial Overgrowth. Am J Gastroenterol. 2009;104(5):1327-8.
- Di Caro S, Tao H, Grillo A, et al. Bacillus clausii effect on gene expression pattern in small bowel mucosa using DNA microarray analysis. Eur J Gastroenterol Hepatol. 2005;17(9):951-60.
- Ciprandi G, Tosca MA, Milanese M, et al. Cytokines evaluation in nasal lavage of allergic children after Bacillus clausii administration: A pilot study. Pediatr Allergy Immunol. 2004;15(2):148-51.
- Casula G, Cutting SM. Bacillus Probiotics: Spore Germination in the Gastrointestinal Tract. App Environ Microb. 200
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