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Oreganum Plus (Oil of Oregano), 60 Gel Caps, St Francis

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Oil of Oregano is a herbal supplement that supports immunity.


  • Immunity– Colds, Flu, Respiratory Health, Sinus and Candida
  • Digestion – Colitis, SIBO, Parasites, Leaky Bowel
  • Health – Cholesterol, Cancer, Weight

Feature Ingredients

  • Oil of Oregano – contains powerful antioxidant and anti-inflammatory properties. Its therapeutic compounds include: carvacrol, thymol and rosmarinic acid that have been found to support immunity.1-3
  • Additional supportive ingredients include garlic and black seed oil.

Oregano oil comes from the leaves and shoots of the oregano plant. Botanically known as Origanum vulgare, oregano is a flowering plant from the same family as mint. It is often used as a herb to flavour food. Oil of oregano contains several potentially healing compounds, such as phenols, terpenes, and terpenoids which have powerful antioxidant properties.

  • Carvacrol: The most abundant phenol in oregano oil. It has been shown to stop the growth of several different types of bacteria.1
  • Thymol: A natural antifungal that can also support the immune system and protect against toxins.Rosmarinic acid: A powerful antioxidant that helps protect against damage caused by free radicals.3

These compounds are thought to underlie oregano's many health benefits. Oil of Oregano has been found to have the following properties:

  • Antimicrobial – Research shows that oil of oregano has antimicrobial, antiviral and antifungal properties.Preliminary research indicates that oil of oregano may be useful for the prevention of Staphylococcus aureus (causes common skin infections); Pseudomonas, E. coli infections (which are common causes of respiratory and urinary tract infections) and bacterial dysentery that causes digestive symptoms.4,5,6 In addition compounds in oregano oil are also a potent antioxidant, anti-inflammatory, antidiabetic, and cancer-suppressor agents.1
  • Colitis – A combination of thyme and oregano oils shows promise in the treatment of colitis, a type of inflammatory bowel disease (IBD).7 An animal-based study found that the inflammation of colitis was significantly reduced after the use of the combination of oils.7
  • Candida – Scientists have found in laboratory research that oil of oregano may fight the growth of candida.8 Candida is a type of yeast that is normally present in the digestive tract and vagina. When it overgrows it can contribute to a number of infections including oral thrush, skin infections, and vaginal yeast infections.8
  • SIBO (Small Intestinal Bacterial Overgrowth) – Oil of oregano along with other herbals may be as effective for SIBO than the commonly used antibiotic Rifaximin.9
  • Parasites – Oil of oregano may help digestive symptoms like bloating, pain, diarrhoea and or constipation that is linked to parasitic overgrowth.10 One study gave 600 mg of oregano oil to 14 people who had gut symptoms as a result of a parasite. After daily treatment for six weeks, all participants experienced a reduction in parasites, and 77% were completely cured.10
  • Leaky Bowel – Early animal research suggests that oil of oregano may help to heal intestinal lining cells.11
  • Cholesterol – Oregano oil has been shown to lower cholesterol in human and animal studies in those with high cholesterol.12 This is thought to be the result of the compounds carvacrol and thymol found in it.12
  • Cancer – Preliminary research has shown that the most abundant compound in oregano oil, carvacrol, inhibits cancer cell growth in lung, liver and breast cancer cells.13-16
  • Weight – Oil of oregano may play a role in weight loss, complimenting a healthy diet and lifestyle.17 In one animal study, those animals given carvacrol along with their high-fat diet gained significantly less weight and body fat compared to those just given a high-fat diet. In addition, carvacrol appeared to reduce the formation of fat cells.17 

Additional human trials are needed to continue to understand the full benefits of oil of oregano therapeutically.

Serving Size: 1 vegetarian gel cap

Servings per Container: 60

Medicinal Ingredients

Medicinal Ingredients (per 500 mg gelcap):

Distilled garlic oil (Allium sativum) 1 mg (alcohol-free)

Non-Medicinal Ingredients

  • Origanum vulgare (Oregano) Leaf Oil 75 mg
  • Nigella sativa (Black Seed) Oil 424 mg
  • Gelatin


Contains No Added: gluten, soy or GMOs. Suitable for vegetarians.

Recommended Use

Adults 19+: Take 1-2 gelcaps twice daily. Consult with a health care practitioner for use beyond 10 days.

St Francis Advantage

Their company has such a solid reputation for authentic craftsmanship and integrity. Their secret abiding respect for traditional herbal knowledge that has been honed over thousands of years, and an unshakeable belief that the way herbal medicines are made matters. 


Do not use if you are hypersensitive or allergic to any of the ingredients (including to plants in the Lamiaceae family, which includes basil, mint, rosemary, sage, savory, marjoram, oregano, hyssop, thyme, lavender and perilla), during pregnancy or breast-feeding.


Consult a health care practitioner prior to use if you are taking any medications)(especially blood thinners or protease inhibitors), or if you have any pre-existing condition including but not limited to: autoimmune disorder, bleeding disorder, diabetes, kidney or liver disease.  Note oil of oregano may reduce the absorption of copper, iron, and/or zinc.

Discontinue 2 weeks prior to any scheduled surgery.  

Side Effect Risks 

Discontinue use and consult a healthcare practitioner if symptoms persist, worsen or you develop any reactions which may include: allergy or intolerance, digestive (stomach upset, irritation of the intestinal tract, heartburn). Note when used topically, oregano essential oil should always be diluted as it may cause burning and skin irritation.

Keep out of reach of children. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place. 


The information and product descriptions that appear on this website are for information and educational purposes only and are not intended to provide or replace medical advice to individuals from qualified health care professionals. Consult your physician if you have any health concerns, and before initiating any new dietary, exercise, supplements or other lifestyle changes.


  1. Leyva-Lopez, N et al, Essential Oils of Oregano: Biological Activity beyond Their Antimicrobial Properties, Molecules 2017, 22(6), 989;
  2. de Castro, R.D., et al. Antifungal activity and mode of action of thymol and its synergism with nystatin against Candida species involved with infections in the oral cavity: an in vitro study. BMC Complement Altern Med 15, 417 (2015).
  3. Bakota EL, et al, Antioxidant activity and sensory evaluation of a rosmarinic acid-enriched extract of Salvia officinalis. J Food Sci. 2015 Apr;80(4):C711-7, doi: 10.1111/1750-3841.12837. Epub 2015 Mar 21.
  4. Preuss, HG, Effects of Essential Oils and Monolaurin on Staphylococcus aureusIn Vitro and In Vivo Studies, J Toxicology Mechanisms and Methods, 2005, 15(4), 279-285 |Published online: 09 Oct 2008
  5. Liao F, et al, Experimental study on the antibacterial effect of origanum volatile oil on dysentery bacilli in vivo and in vitro. J Huazhong Univ Sci Thenolog Med Sci. 2004;24(4):400-3.
  6. Sienkiewicz M, et al, [The antibacterial activity of oregano essential oil (Origanum heracleoticum L.) against clinical strains of Escherichia coli and Pseudomonas aeruginosa].Med Dosw Mikrobiol. 2012;64(4):297-307
  7. Bukovska A, et al, Effects of a Combination of Thyme and Oregano Essential Oils on TNBS-Induced Colitis in Mice, J of Hindawai, Mediators of Inflammation, 2007, Article ID 23296,
  8. Cleff MB, et al, In vitro activity of origanum vulgare essential oil against candida species, Braz J Microbiol. 2010 Jan-Mar; 41(1):116-123.
  9. Chedid, V, et al, Herbal Therapy Is Equivalent to Rifaximin for the Treatment of Small Intestinal Bacterial Overgrowth, Glob Adv Health Med. 2014 May; 3(3):16-24
  10. Force M, Sparks WS, Ronzio RA, Inhibition of enteric parasites by emulsified oil of oregano in vivo. Phytother Res. 2000 May;14(3):213-4.
  11. Zou Y, et al, Oregano Essential Oil Improves Intestinal Morphology and Expression of Tight Junction Proteins Associated with Modulation of Selected Intestinal Bacteria and Immune Status in a Pig Model, Biomed Res Int. 2016; 2016: 5436738
  12. Kulisic T et al, The effects of essential oils and aqueous tea infusions of oregano (Origanum vulgare L. spp. hirtum), thyme (Thymus vulgaris L.) and wild thyme (Thymus serpyllum L.) on the copper-induced oxidation of human low-density lipoproteins. Int J Food Sci Nutr. 2007 Mar;58(2):87-93.
  13. Koparal, AT, and Zeytinouglu M, Effects of Carvacrol on a Human Non-Small Cell Lung Cancer (NSCLC) Cell Line, A549, Cytotechnology. 2003 Nov;43(1-3):149-154.
  14. Yin Q-h, et al, Anti-proliferative and pro-apoptotic effect of carvacrol on human hepatocellular carcinoma cell line HepG-2, Cytotechnology. 2012 Jan;64(1):43-51.
  15. Arunasree KM, Anti-proliferative effects of carvacrol on a human metastatic breast cancer cell line, MDA-MB 231., Phytomedicine. 2010 Jul;17(8-9):581-8.
  16. Cho S, et al, Carvacrol prevents diet-induced obesity by modulating gene expressions involved in adipogenesis and inflammation in mice fed with high-fat diet. J Nutr Biochem. 2012 Feb; 23(2): 192-201