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Improves overall sleep & helps with jet lag
- The most comprehensive, natural sleep formula available
- Helps one fall asleep, stay asleep and wake up feeling refreshed
- Increase total sleep time for those with sleep restrictions ( shift work, jet-lag) to reset circadian rhythm
- Bronze winner of the 2013 Optimyz Best of the Best Awards
Did you know that irregular sleep patterns are being called the new silent killer, being as detrimental to health as stress and poor diet? Studies show that those who chronically get less sleep than the “golden” seven to eight hours are at a higher risk for a number of diseases, are prone to weight gain, and are less able to deal with the effects of stress. People suffering from insomnia spend less time in deeper levels of sleep, wake up more often, and experience a reduction in REM sleep. In addition to stress, insomnia can be caused by a variety of other factors, including anxiety, poor diet, or a disruption of the body’s internal clock – such as jet lag, all-night study sessions, or changing work hours.
Ortho Sleep™ is an award-winning premium sleep and relaxation formula. The most important neurotransmitters known to regulate the sleep-wake cycle have been combined with the most powerful herbs traditionally used to promote sleep, yielding a natural sleep remedy like no other. Ortho Sleep™ contains a carefully formulated blend of nutrients and compounds that have been shown to be effective in combating insomnia, restoring a proper circadian rhythm and promoting healthy, restful sleep. These include relaxing neurotransmitters GABA and melatonin, as well as 5-HTP, a serotonin precursor to reduce feelings of worry, especially when trying to fall asleep. The formula further includes the amino acid L-theanine as well as valerian root, passionflower extract and lemon balm, all of which possess relaxing properties and work to increase the activity of GABA in the brain.
Ortho Sleep™ is perfect for those who have difficulty falling asleep, staying asleep, or feeling rested upon waking. Ortho Sleep™ may help in cases of jet-lag, shift work or insomnia. If you have used the individual ingredients found in the formula with no success, Ortho Sleep™ may offer a more powerful natural solution
AOR Advantage
AOR’s DGL-760 is ideal for anyone suffering from symptoms of bowel inflammation such as abdominal cramping, heartburn, bloating, gas, diarrhea and constipation. DGL-760 reduces the risk of developing ulcers without the blood pressure raising effects of other licorice supplements.
- Deglycyrrhizinated licorice, or DGL, has been used clinically for decades, primarily for the treatment of peptic ulcers.1
- Licorice has been shown to inhibit several inflammatory enzymes, including both cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX), decreasing the production of several potent inflammatory compounds, including prostaglandin E2, thromboxane B2, and leukotriene B4.
- Importantly, this inhibition is not due to glycyrrhizic acid, the component of licorice which has been removed in DGL, and which is associated with mineralocorticoid excess and hypertension.2
- Another component of licorice, glabridin, has been shown to prevent lipopolysaccharide (LPS) induced production of inflammatory compounds, including nitric oxide and interleukin-1 beta, whereas glycyrrhizic acid has no effect.
- Clinically, DGL has been shown to have comparable efficacy to cimetidine for both the healing and prevention of ulcer recurrences.3
- Additionally, extracts of licorice have been shown to inhibit the adhesion of H. pylori to gastric mucosa, as well as the growth of antibiotic resistant strains, suggesting multiple mechanisms of action for its anti-ulcer benefit.4,5 The use of chewable tablets appears necessary for DGL’s efficacy, as it allows for distribution and absorption by the gastric mucosa.3
Non-medicinal Ingredients*: maltodextrin (corn), gum arabic, silicon dioxide, sodium stearyl fumarate. Capsule: hypromellose.
*NMIs are subject to change. Always read and follow the label for accurate ingredient and allergen information.
Allergens
AOR™ guarantees that all ingredients have been declared on the label. Contains no wheat, gluten, nuts, peanuts, sesame seeds, sulphites, mustard, soy, dairy, eggs, fish, shellfish or any animal by-product.
Recommended Use
Adults 19+: Take one to two capsules before bedtime with or without food, or as directed by a qualified health care practitioner.
AOR Advantage
AOR puts pharmaceutical principles into practice to create the most effective products with the highest quality raw materials. Our processes allow us to ensure potency, purity and traceability from plant to product, giving our customers the certainty that they are always getting the same, effective formulation. We introduce and implement the latest testing strategies as part of our quality assurance process because we believe that it’s not about checking boxes, but how the boxes are checked that is important.
Contraindications
Do not use if you are hypersensitive or allergic to any of the ingredients. Do not use if you are pregnant or breastfeeding, have impaired kidney or liver functions, high blood pressure or heart disease or are a man with decreased libido.
Caution
Do not take Ortho Sleep™ if pregnant, breastfeeding, trying to conceive, or taking immunosuppressive drugs. Not to be used by individuals under the age of 18 or those with a medical condition. Do not use if you have scleroderma.
Consult a health care practitioner prior to use if taking sedatives, hypnotic medication, psychotropic medications, blood pressure medication, anticoagulant, anticonvulsant, steroids, carbidopa or drugs/supplements with serotonergic activity. These may include, but are not limited to, L-tryptophan, S-adenosylmethionine (SAMe), St. John’s Wort, antidepressants, pain killers, cough/cold medication containing dextromethorphan, anti-nausea, anti-blood pressure and anti-migraine medication. Discontinue use and consult a health care practitioner if you show signs of weakness, oral ulcers, or abdominal pain accompanied by severe muscle pain or if you experience skin changes. Mild gastrointestinal symptoms (e.g. nausea, vomiting, or cramping) and hypersensitivity (e.g. allergy) has been known to occur; in which case, discontinue use. Some people may experience drowsiness. Do not drive or use machinery for five hours after taking Ortho Sleep™. Exercise caution if engaging in activities requiring mental alertness. Consult a health care practitioner prior to use if you have asthma, cardiovascular disease, immune system disease, hormonal disorder, diabetes or hypoglycaemia, liver or chronic kidney disease, cerebral palsy, seizure disorders, migraine, depression and/or hypertension, if sleeplessness persists continuously for more than three weeks, chronic insomnia or if symptoms persist or worsen. Consumption with alcohol, other medications or health products with sedative properties is not recommended.
Side Effect Risks
Discontinue use and consult a healthcare practitioner if symptoms persist, worsen or you develop any reactions which may include: allergy or intolerance. Keep out of reach of children. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.
Disclaimer
The information and product descriptions that appear on this website are for information and educational purposes only and are not intended to provide or replace medical advice to individuals from qualified health care professionals. Consult your physician if you have any health concerns, and before initiating any new dietary, exercise, supplements or other lifestyle changes.
References
- Turpie AG, et al. Clinical trial of deglydyrrhizinized liquorice in gastric ulcer. Gut. 1969 Apr;10(4):299-302.
- Chandrasekaran CV, et al. Dual inhibitory effect of Glycyrrhiza glabra (GutGard™) on COX and LOX products. Phytomedicine. 2011 Feb 15;18(4):278-84.
- Morgan AG, et al. Comparison between cimetidine and Caved-S in the treatment of gastric ulceration, and subsequent maintenance therapy. Gut. 1982 Jun;23(6):545-51.
- Wittschier N, et al. Aqueous extracts and polysaccharides from liquorice roots (Glycyrrhiza glabra L.) inhibit adhesion of Helicobacter pylori to human gastric mucosa. J Ethnopharmacol. 2009 Sep 7;125(2):218-23.
- Fukai T, et al. Anti-Helicobacter pylori flavonoids from licorice extract. Life Sci. 2002 71:1449-63.
