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CoQ10 (Coenzyme Q10) and PQQ (Pyrroloquinoline Quinone) are antioxidants which help support oxidative stress and mitochondrial function.
Supports
- Nutrients - antioxidants
-
Longevity & Energy - mitochondrial function, cellular aging, cardiovascular health
-
Fertility
Feature Ingredients
- BioPQQ® is manufactured in Japan using a patented natural fermentation process to enhance absorption – derived from 100% all-natural sourced materials
-
PQQ has synergistic activity when combined with CoQ10,
providing optimal mitochondrial function and energy production
PQQ and CoQ10 are antioxidants which are synergistic nutrients which modulate cellular signalling pathways, neutralize reactive oxygen species, and support optimal mitochondrial function.
- Mitochondrial dysfunction and oxidative stress are involved in an ever-increasing range of conditions and are thought to play important roles in egg and sperm quality, as well as cellular aging. CoQ10 is well established as a mitochondrial enhancer, with proven benefit in the treatment and prevention of numerous cardiovascular and neurological conditions.
- CoQ10 also affects oocyte mitochondrial function, sperm quality, and fertility.1,2
- CoQ10 increases the efficiency of mitochondrial ATP production and cellular respiration.3
- PQQ is a novel biofactor, known to influence multiple cellular pathways, including the production of nerve growth factor (NGF).
- PQQ has diverse benefit for mitochondrial function, and has been shown to attenuate mitochondrial oxidative stress as well as to stimulate mitochondrial biogenesis.4
- It also has neuroprotective properties including protection against glutamate-induced toxicity, a pathway common in many neurodegenerative diseases. BioPQQ is considered a novel cofactor with antioxidant and B vitamin-like activity. It is naturally fermented to enhance absorption.5
- Addresses mitochondrial dysfunction and oxidative stress, key determinants of oocyte and sperm quality
- Formulated with vitamin E derived from non-GMO sunflower lecithin
Serving Size: 1 Softgel
Servings per Container: 60
Medicinal Ingredients
| Each Softgel Contains: | |
| Coenzyme Q10 (Microorganism) | 200 mg |
| PQQ (BioPQQ® Pyrroloquinoline Quinone Disodium Salt) | 20 mg |
| (Providing Pyrroloquinoline Quinone 17 .65 mg) | |
| Vitamin E (Natural d-alpha Tocopherol) (SUN-E 900) (Non-GMO Sunflower Oil) | 5 IU (3 .35 mg AT |
Non-Medicinal Ingredients
Organic flaxseed oil, softgel (gelatin, glycerin, purified water, carob), yellow beeswax, non-GMO sunflower lecithin.
Allergens
Contains No Added: artificial colours, preservatives, or sweeteners; dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, salt, tree nuts, or GMOs.
Recommended Use
Adults 19+: 1 softgel daily with food or as directed by a health care practitioner
Bioclinic Naturals Advantage
Highly bioavailable ingredients for optimal absorption.
Contraindications
Do not use if you are hypersensitive or allergic to any of the ingredients.
Caution
Consult a health care practitioner prior to use if you are taking any medications, or if you have any pre-existing condition including but not limited to pregnancy or breastfeeding. Discontinue this product 2 weeks prior to surgery.
Side Effect Risks
Discontinue use and consult a healthcare practitioner if symptoms persist, worsen or you develop any reactions which may include: allergy or intolerance. Keep out of reach of children. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.
Disclaimer
The information and product descriptions that appear on this website are for information and educational purposes only and are not intended to provide or replace medical advice to individuals from qualified health care professionals. Consult your physician if you have any health concerns, and before initiating any new dietary, exercise, supplements or other lifestyle changes.
References
- Ben-Meir, A., Burstein, E., Borrego-Alvarez, A., et al. (2015). Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging. Aging Cell, 14(5), 887-95.
- Safarinejad, M.R., Safarinejad, S., Shafiei, N., et al. (2012). Effects of the reduced form of coenzyme Q10 (ubiquinol) on semen parameters in men with idiopathic infertility: a doubleblind, placebo controlled, randomized study. J Urol, 188(2), 526-31.
- Takeda, R., Sawabe, A., Nakano, R., et al. (2011). Effect of various food additives and soy constituents on high CoQ10 absorption. Japanese Journal Medicine Pharmaceutical Science, 64(4), 614-20.
- Chowanadisai, W., Bauerly, K.A., Tchaparian, E., et al. (2010). Pyrroloquinoline quinone stimulates mitochondrial biogenesis through cAMP response element-binding protein phosphorylation and increased PGC-1alpha expression. J Biol Chem, 285(1), 142-52.
- Rucker, R., Chowanadisai, W., Nakano, M. (2009). Potential physiological importance of pyrroloquinoline quinone. Altern Med Rev, 14(3), 268-77.
- Nakano, M., Ubukata, K., Yamamoto, T., et al. (2009). Effect of pyrroloquinoline quinone (PQQ) on mental status of middle-aged and elderly persons. Food Style, 13(7), 50-3.
- Littarru, G.P., Tiano, L., Belardinelli, R., et al. (2011). Coenzyme Q(10), endothelial function and cardiovascular disease. Biofactors, 37(5), 366-73.
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