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Somno-Pro, 90 Chew Tabs

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This formula helps all aspects of sleep challenges.  Delicious tropical fruit-flavoured chewable tablets.

      Supports

      • Insomnia - difficulty initiating sleep, difficulty maintaining sleep, waking too early in the morning, and waking groggy
      • Nervousness - reduces nervous system excitation, which can inhibit sleep

        Feature Ingredients

        • Contains Suntheanine®, the most clinically studied L-theanine
        • Supported with 5-HTP the precursor to serotonin and melatonin.

                        L-Theanine, 5-hydroxytryptophan (5-HTP) and melatonin have all been shown to independently improve sleep quality and quantity, and/or lessen anxiety.

                        • L-Theanine is an amino acid found almost exclusively in tea,1 which influences the central nervous system through a number of mechanisms, primarily by influencing levels of the neurotransmitters dopamine,2 gamma-aminobutyric acid (GABA),3,4 serotonin,5,6 norepinephrine6 and glutamate.7,8 These effects cause a significant increase in alpha brain wave activity, indicative of a state of wakeful relaxation, increased performance under stress, improved learning and concentration, as well as decreased anxiety.1,9
                        • 5-HTP is the intermediary between L-tryptophan and serotonin, a key neurotransmitter associated with sleep, mood, and anxiety.10-12 5-HTP bypasses the rate limiting enzyme tryptophan hydroxylase, which normally limits the conversion of tryptophan to serotonin.13
                        • Melatonin is also closely related, and is formed by conversion of serotonin in the pineal gland. Known to regulate many biological rhythms, including the circadian cycle, melatonin has shown clinical benefit for inducing sleep or adjusting sleep cycles.14 Randomized trials have found it to reduce sleep onset latency and improve perceived quality of sleep, without impairing daytime psychomotor performance.15,16

                              Service Size: 2 Chew Tabs

                              Servings per Container:  45

                              Medicinal Ingredients

                              Each Tablet Contains:
                              Suntheanine® L-Theanine 100 mg
                              L-5-Hydroxytryptophan (5-HTP) (Griffonia simplicifolia) (seed) 15 mg
                              Melatonin 1.5 mg

                              Non-Medicinal Ingredients

                              Organic cane juice, stearic acid, xylitol, silica, natural flavours, citric acid, vegetable grade magnesium stearate (lubricant).

                              Allergens

                              Contains No Added: artificial colours, preservatives, or sweeteners; dairy, wheat, gluten, yeast, soy,  egg, fish, shellfish, animal products, salt, tree nuts, or GMOs.  Suitable for Vegetarians/Vegans.

                              Recommended Use

                              Adults 19+: Chew 2 tablets once per day before bedtime or as directed by a health care practitioner. Some people may experience drowsiness . Exercise caution if involved in activities requiring mental alertness. Do not drive or use machinery for 5 hours after taking melatonin. Consult a health care practitioner for use beyond 4 weeks.

                              Bioclinic Naturals Advantage

                              Highly bioavailable ingredients for optimal absorption.

                              Contraindications

                              Do not use if you are hypersensitive or allergic to any of the ingredients, pregnant, breastfeeding, taking blood pressure, immunosuppressive, sedative/hypnotic medication, and or have scleroderma.

                              Caution

                              Consult a health care practitioner prior to use if you are taking any medications or if you have any pre-existing condition.  Discontinue this product 2 weeks prior to surgery.

                              L-theanine is known to have a hypotensive effect in some individuals, and concomitant use of antihypertensive drugs may potentiate their activity.17

                              Side Effect Risks

                              Discontinue use and consult a healthcare practitioner if symptoms persist, worsen or you develop any reactions which may include: allergy or intolerance or drowsiness. Do not drive or operate heavy machinery for 5 hours after using this product. Exercise caution if involved in activities requiring mental alertness. Discontinue use if you show signs of weakness, oral ulcers, or abdominal pain accompanied by severe muscle pain, or if you experience skin changes. Keep out of reach of children. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.

                              Disclaimer

                              The information and product descriptions that appear on this website are for information and educational purposes only and are not intended to provide or replace medical advice to individuals from qualified health care professionals. Consult your physician if you have any health concerns, and before initiating any new dietary, exercise, supplements or other lifestyle changes.

                              References

                              1. . Juneja, L.R., Chu, D.C., Okubo, T., et al. (1999). L-Theanine – a unique amino acid of green tea and its relaxation effect in humans. Trends in Food Science &Technology, 10(2), 199-204.
                              2. Yokogoshi, H., Kobayashi, M., Mochizuki, M., et al. (1998). Effect of theanine, r-glutamylethylamide, on brain monoamines and striatal dopamine release in conscious rats. Neurochem Res, 23(5), 667-73.
                              3. Kimura, R., Murata, T. (1971). Influence of alkylamides of glutamic acid and related compounds on the central nervous system. I. Central depressant effect of theanine. Chem Pharm Bull, (Tokyo), 19(6), 1257-61.
                              4. Alternative Medicine Review. Gamma-Aminobutyric Acid (GABA), Monograph. (2007). Altern Med Rev, 12(3), 274-9.
                              5. Yokogoshi, H., Mochizuki, M., Saitoh, K. (1998). Theanine-induced reduction of brain serotonin concentration in rats. Biosci Biotechnol Biochem, 62(4), 816-7.
                              6. Kimura, R., Murata, T. (1986). Effect of theanine on norepinephrine and serotonin levels in rat brain. Chem Pharm Bull (Tokyo), 34(7), 3053-7.
                              7. Kakuda T. (2002). Neuroprotective effects of green tea components theanine and catechins. Biol Pharm Bull, 25(12), 1513-8.
                              8. Kimura, K., Ozeki, M., Juneja, L.R., et al. (2007). L-theanine reduces psychological and physiological stress responses. Biol Psychol, 74(1), 39-45.
                              9. Nobre, A.C, Rao, A., Owen, G.N. (2008). L-theanine, a natural constituent in tea, and its effect on mental state. Asia Pac J Clin Nutr, 17 Suppl, 167-8
                              10. Birdsall, T.C. (1998). 5-Hydroxytryptophan: a clinically effective serotonin precursor. Altern Med Rev, 3(4), 271-80.
                              11. Wyatt, R.J., Zarcone, V., Engelman, K., et al. Effects of 5-hydroxytryptophan on the sleep of normal human subjects. Electroencephalogr Clin Neurophysiol, 30(6), 505-9.
                              12. Soulairac, A., Lambinet, H. (1998). Clinical studies of the effect of the serotonin precursor, L-5-Hydroxytryptophan, on sleep disorders. Schweiz Rundsch Med Prax, 77(34A), 19-23.
                              13. Shaw, K., Turner, J., Del Mar, C. (2002). Tryptophan and 5-hydroxytryptophan for depression. Cochrane Database Syst Rev, (1), CD003198.
                              14. Kunz, D., Mahlberg, R., Muller, C., et al. (2004). Melatonin in patients with reduced REM sleep duration: two randomized controlled trials. J Clin Endocrinol Metab, 89(1), 128-34.
                              15. Wade, A.G., Ford, I., Crawford, G., et al. (2007). Efficacy of prolonged release melatonin in insomnia patients aged 55–80 years: quality of sleep and next day alertness outcomes. Curr Med Res Opin, 23(10), 2597-605.
                              16. Wade, A.G., Ford, I., Crawford, G., et al. (2010). Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety. BMC Med, 8, 51.
                              17. Yokogoshi, H., Kobayashi. M. (1998). Hypotensive effect of gamma-glutamylmethylamide ontaneously hypertensive rats. Life Sci, 62(12), 1065-8.